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Lack of effect of genetic polymorphisms of SLCO1B1 on the lipid-lowering response to pitavastatin in Chinese patients

AIM: To investigate the SLCO1B1 388A>G and 521T>C polymorphisms in hyperlipidemia patients and evaluate the effect of the two polymorphisms on the lipid-lowering efficacy of pitavastatin. METHODS: The functional polymorphisms of SLCO1B1 (388A>G and 521T>C) were genotyped in 140 Chinese p...

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Hlavní autoři: Yang, Guo-ping, Yuan, Hong, Tang, Bin, Zhang, Wei, Wang, Lian-sheng, Huang, Zhi-jun, Ou-Yang, Dong-sheng, Zhang, Gui-xiang, Zhou, Hong-hao
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002408/
https://ncbi.nlm.nih.gov/pubmed/20140004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.203
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