Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy

Products of proto-oncogenes c-MET and RON belong to a subfamily of receptor tyrosine kinases that contribute significantly to tumorigenic progression. In primary tumors, altered c-MET/RON expression transduces signals regulating invasive growth that is characterized by cell migration and matrix inva...

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Detalhes bibliográficos
Main Authors: Wang, Ming-Hai, Padhye, Snehal S, Guin, Sunny, Ma, Qi, Zhou, Yong-qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002297/
https://ncbi.nlm.nih.gov/pubmed/20694025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.106
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