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MET and RON receptor tyrosine kinases in colorectal adenocarcinoma: molecular features as drug targets and antibody-drug conjugates for therapy

Advanced colorectal adenocarcinoma (CRAC), featured by distinctive histopathological appearance, distant organ metastasis, acquired chemoresistance, and tumorigenic stemness is a group of heterogeneous cancers with unique genetic signatures and malignant phenotypes. Treatment of CRAC is a daunting t...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Yao, Hang-Ping, Tong, Xiang-Min, Hudson, Rachel, Wang, Ming-Hai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510328/
https://ncbi.nlm.nih.gov/pubmed/32962738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01711-x
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