The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells

BACKGROUND: Overexpression of the RON receptor tyrosine kinase contributes to epithelial cell transformation, malignant progression, and acquired drug resistance. RON also has been considered as a potential target for therapeutic intervention. This study determines biochemical features and inhibitor...

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Detalhes bibliográficos
Main Authors: Yao, Hang-Ping, Zhou, Yong-Qing, Ma, Qi, Guin, Sunny, Padhye, Snehal S, Zhang, Rui-Wen, Wang, Ming-Hai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142532/
https://ncbi.nlm.nih.gov/pubmed/21749705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-82
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