The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells

BACKGROUND: Overexpression of the RON receptor tyrosine kinase contributes to epithelial cell transformation, malignant progression, and acquired drug resistance. RON also has been considered as a potential target for therapeutic intervention. This study determines biochemical features and inhibitor...

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Main Authors: Yao, Hang-Ping, Zhou, Yong-Qing, Ma, Qi, Guin, Sunny, Padhye, Snehal S, Zhang, Rui-Wen, Wang, Ming-Hai
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142532/
https://ncbi.nlm.nih.gov/pubmed/21749705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-82
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