Berbamine exhibits potent antitumor effects on imatinib-resistant CML cells in vitro and in vivo

AIM: The aim of this study was to explore the effects and mechanism of berbamine on imatinib-resistant BCR-ABL-positive human leukemia K562 (K562-r) cells in vitro and in vivo. METHODS: Cell viability was measured by MTT assay, and apoptotic morphology changes were detected by fluorescence microscop...

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Detalhes bibliográficos
Main Authors: Wei, Yan-lin, Xu, Lei, Liang, Yun, Xu, Xiao-hua, Zhao, Xiao-ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002272/
https://ncbi.nlm.nih.gov/pubmed/19270722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.19
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