Tetrandrine citrate eliminates imatinib-resistant chronic myeloid leukemia cells in vitro and in vivo by inhibiting Bcr-Abl/β-catenin axis

Objective: To evaluate the effects of tetrandrine citrate, a novel tetrandrine salt with high water solubility, on the growth of imatinib (IM)-resistant chronic myeloid leukemia (CML) in vitro and in vivo, and reveal action molecular mechanisms. Methods: Cell viability in vitro was measured using me...

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Detalhes bibliográficos
Main Authors: Xu, Xiao-hua, Gan, Yi-chao, Xu, Gen-bo, Chen, Ting, Zhou, Hong, Tang, Jin-fen, Gu, Ying, Xu, Fei, Xie, Ying-ying, Zhao, Xiao-ying, Xu, Rong-zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2012
Assuntos:
Biomedicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494025/
https://ncbi.nlm.nih.gov/pubmed/23125079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1200021
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