Inhibition of YAP suppresses CML cell proliferation and enhances efficacy of imatinib in vitro and in vivo

BACKGROUND: Yes-associated protein (YAP), an essential component of Hippo pathway, was identified as an oncoprotein which participated in the progression of various malignancies. However, its role in chronic myeloid leukemia (CML) remains to be further clarified. METHODS: The expression of YAP in CM...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Li, Hui, Huang, Zhenglan, Gao, Miao, Huang, Ningshu, Luo, Zhenhong, Shen, Huawei, Wang, Xin, Wang, Teng, Hu, Jing, Feng, Wenli
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012077/
https://ncbi.nlm.nih.gov/pubmed/27599610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0414-z
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