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Proteasomes Associated with the Blm10 Activator Protein Antagonize Mitochondrial Fission through Degradation of the Fission Protein Dnm1

The conserved Blm10/PA200 activators bind to the proteasome core particle gate and facilitate turnover of peptides and unfolded proteins in vitro. We report here that Blm10 is required for the maintenance of functional mitochondria. BLM10 expression is induced 25-fold upon a switch from fermentation...

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書誌詳細
主要な著者: Tar, Krisztina, Dange, Thomas, Yang, Ciyu, Yao, Yanhua, Bulteau, Anne-Laure, Salcedo, Elena Fernandez, Braigen, Stephen, Bouillaud, Frederic, Finley, Daniel, Schmidt, Marion
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002118/
https://ncbi.nlm.nih.gov/pubmed/24604417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554105
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