Proteasomes Associated with the Blm10 Activator Protein Antagonize Mitochondrial Fission through Degradation of the Fission Protein Dnm1

The conserved Blm10/PA200 activators bind to the proteasome core particle gate and facilitate turnover of peptides and unfolded proteins in vitro. We report here that Blm10 is required for the maintenance of functional mitochondria. BLM10 expression is induced 25-fold upon a switch from fermentation...

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Bibliografiska uppgifter
Huvudupphovsmän: Tar, Krisztina, Dange, Thomas, Yang, Ciyu, Yao, Yanhua, Bulteau, Anne-Laure, Salcedo, Elena Fernandez, Braigen, Stephen, Bouillaud, Frederic, Finley, Daniel, Schmidt, Marion
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002118/
https://ncbi.nlm.nih.gov/pubmed/24604417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554105
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