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T-type Channels Become Highly Permeable to Sodium Ions Using an Alternative Extracellular Turret Region (S5-P) Outside the Selectivity Filter
T-type (Ca(v)3) channels are categorized as calcium channels, but invertebrate ones can be highly sodium-selective channels. We illustrate that the snail LCa(v)3 T-type channel becomes highly sodium-permeable through exon splicing of an extracellular turret and descending helix in domain II of the f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002102/ https://ncbi.nlm.nih.gov/pubmed/24596098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551473 |
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