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Luciferase does not Alter Metabolism in Cancer Cells

Luciferase transfected cell lines are used extensively for cancer models, revealing valuable biological information about disease mechanisms. However, these genetically encoded reporters, while useful for monitoring tumor response in cancer models, can impact cell metabolism. Indeed firefly lucifera...

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Detalhes bibliográficos
Main Authors: Johnson, Caroline H., Fisher, Timothy S., Hoang, Linh T., Felding, Brunhilde H., Siuzdak, Gary, O’Brien, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002053/
https://ncbi.nlm.nih.gov/pubmed/24791164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-014-0622-5
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