Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging

BACKGROUND: Tissue imaging of treatment-induced metabolic changes is useful for optimizing cancer therapies, but commonly used methods require trade-offs between assay sensitivity and spatial resolution. Nanostructure-Initiator Mass Spectrometry imaging (NIMS) permits quantitative co-localization of...

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Detalhes bibliográficos
Main Authors: O’Brien, Peter J, Lee, Michelle, Spilker, Mary E, Zhang, Cathy C, Yan, Zhengming, Nichols, Timothy C, Li, Wenlin, Johnson, Caroline H, Patti, Gary J, Siuzdak, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834492/
https://ncbi.nlm.nih.gov/pubmed/24280026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-4
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