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Effects of diltiazem and propafenone on the inactivation and recovery kinetics of fKv1.4 channel currents expressed in Xenopus oocytes

AIM: To investigate the effects of diltiazem, an L-type calcium channel blocker, and propafenone, a sodium channel blocker, on the inactivation and recovery kinetics of fKv1.4, a potassium channel that generates the cardiac transient outward potassium current. METHODS: The cRNA for fKv1.4ΔN, an N-te...

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Bibliografske podrobnosti
Main Authors: Zhang, Dong, Wang, Shi-min, Chen, Hui, Jiang, Xue-jun, Chao, Sheng-ping
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001977/
https://ncbi.nlm.nih.gov/pubmed/21468083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.234
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