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C-Type inactivation involves a significant decrease in the intracellular aqueous pore volume of Kv1.4 K(+) channels expressed in Xenopus oocytes
Channels are water-filled membrane-spanning proteins, which undergo conformational changes as they gate, i.e. open or close. These conformational changes affect both the shape of the channel and the volume of the water-filled pore. We measured the changes in pore volume associated with activation, d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2342995/ https://ncbi.nlm.nih.gov/pubmed/12730347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.034660 |
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