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Comparison of the effects of antiarrhythmic drugs flecainide and verapamil on fKv1.4ΔN channel currents in Xenopus oocytes

AIM: To study the effects of Na(+) channel blocker flecainide and L-type Ca(2+) channel antagonist verapamil on the voltage-gated fKv1.4ΔN channel, an N-terminal-deleted mutant of the ferret Kv1.4 K(+) channel. METHODS: fKv1.4ΔN channels were stably expressed in Xenopus oocytes. The K(+) currents we...

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Detalhes bibliográficos
Main Authors: Chen, Hui, Zhang, Dong, Chao, Sheng-ping, Ren, Jiang-hua, Xu, Lin, Jiang, Xue-jun, Wang, Shi-min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011620/
https://ncbi.nlm.nih.gov/pubmed/23202797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.157
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