In Vivo Effect of Mutant ELOVL4 on the Expression and Function of Wild-Type ELOVL4

PURPOSE. Mutations in the elongation of very long chain fatty acids 4 (ELOVL4) gene cause human Stargardt's macular dystrophy 3 (STGD3), a juvenile onset dominant form of macular degeneration. To understand the role of the ELOVL4 protein in retinal function, several mouse models have been devel...

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Main Authors: Mandal, Nawajes A., Tran, Julie-Thu A., Zheng, Lixin, Wilkerson, Joseph L., Brush, Richard S., McRae, Joel, Agbaga, Martin-Paul, Zhang, Kang, Petrukhin, Konstantin, Ayyagari, Radha, Anderson, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001787/
https://ncbi.nlm.nih.gov/pubmed/24644051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13198
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