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Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma
The discovery of activating BRAF V600E mutations in 50% of all cutaneous melanomas has revolutionized the understanding of melanoma biology and provided new strategies for the therapeutic management of this deadly disease. Highly potent small molecule inhibitors of BRAF are now showing great promise...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001781/ https://ncbi.nlm.nih.gov/pubmed/21635872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.05.015 |
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