PD-1 identifies the patient-specific CD8(+) tumor-reactive repertoire infiltrating human tumors

Adoptive transfer of tumor-infiltrating lymphocytes (TILs) can mediate regression of metastatic melanoma; however, TILs are a heterogeneous population, and there are no effective markers to specifically identify and select the repertoire of tumor-reactive and mutation-specific CD8(+) lymphocytes. Th...

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Detalhes bibliográficos
Main Authors: Gros, Alena, Robbins, Paul F., Yao, Xin, Li, Yong F., Turcotte, Simon, Tran, Eric, Wunderlich, John R., Mixon, Arnold, Farid, Shawn, Dudley, Mark E., Hanada, Ken-ichi, Almeida, Jorge R., Darko, Sam, Douek, Daniel C., Yang, James C., Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001555/
https://ncbi.nlm.nih.gov/pubmed/24667641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73639
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