Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway

Transcriptional coregulators are important components of nuclear receptor (NR) signaling machinery and provide additional mechanisms for modulation of NR activity. Expression of a mutated nuclear corepressor 1 (NCoR1) that lacks 2 NR interacting domains (NCoRΔID) in the liver leads to elevated expre...

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Detalhes bibliográficos
Main Authors: Astapova, Inna, Ramadoss, Preeti, Costa-e-Sousa, Ricardo H., Ye, Felix, Holtz, Kaila A., Li, Yingxia, Niepel, Michele W., Cohen, David E., Hollenberg, Anthony N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001554/
https://ncbi.nlm.nih.gov/pubmed/24713658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73419
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