Novel Mechanism of Positive versus Negative Regulation by Thyroid Hormone Receptor β1 (TRβ1) Identified by Genome-wide Profiling of Binding Sites in Mouse Liver

Triiodothyronine (T3) regulates key metabolic processes in the liver through the thyroid hormone receptor, TRβ1. However, the number of known target genes directly regulated by TRβ1 is limited, and the mechanisms by which positive and especially negative transcriptional regulation occur are not well...

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Detaylı Bibliyografya
Asıl Yazarlar: Ramadoss, Preeti, Abraham, Brian J., Tsai, Linus, Zhou, Yiming, Costa-e-Sousa, Ricardo H., Ye, Felix, Bilban, Martin, Zhao, Keji, Hollenberg, Anthony N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Gene Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894317/
https://ncbi.nlm.nih.gov/pubmed/24288132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521450
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