Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection

Respiratory syncytial virus (RSV) infection accounts for approximately 64 million cases of respiratory disease and 200,000 deaths worldwide each year, yet no broadly effective prophylactic or treatment regimen is available. RSV deploys paired, self-associating, heptad repeat domains of its fusion pr...

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Autori principali: Bird, Gregory H., Boyapalle, Sandhya, Wong, Terianne, Opoku-Nsiah, Kwadwo, Bedi, Raminder, Crannell, W. Christian, Perry, Alisa F., Nguyen, Huy, Sampayo, Viviana, Devareddy, Ankita, Mohapatra, Subhra, Mohapatra, Shyam S., Walensky, Loren D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001541/
https://ncbi.nlm.nih.gov/pubmed/24743147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71856
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