Respiratory Syncytial Virus (RSV) Infection in Elderly Mice Results in Altered Antiviral Gene Expression and Enhanced Pathology

Elderly persons are more susceptible to RSV-induced pneumonia than young people, but the molecular mechanism underlying this susceptibility is not well understood. In this study, we used an aged mouse model of RSV-induced pneumonia to examine how aging alters the lung pathology, modulates antiviral...

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Autori principali: Wong, Terianne M., Boyapalle, Sandhya, Sampayo, Viviana, Nguyen, Huy D., Bedi, Raminder, Kamath, Siddharth G., Moore, Martin L., Mohapatra, Subhra, Mohapatra, Shyam S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928298/
https://ncbi.nlm.nih.gov/pubmed/24558422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088764
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