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Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

Inflammatory bowel disease (IBD) pathogenesis is associated with dysregulated CD4(+) Th cell responses, with intestinal homeostasis depending on the balance between IL-17–producing Th17 and Foxp3(+) Tregs. Differentiation of naive T cells into Th17 and Treg subsets is associated with specific gene e...

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Detalhes bibliográficos
Main Authors: Antignano, Frann, Burrows, Kyle, Hughes, Michael R., Han, Jonathan M., Kron, Ken J., Penrod, Nadia M., Oudhoff, Menno J., Wang, Steven Kai Hao, Min, Paul H., Gold, Matthew J., Chenery, Alistair L., Braam, Mitchell J.S., Fung, Thomas C., Rossi, Fabio M.V., McNagny, Kelly M., Arrowsmith, Cheryl H., Lupien, Mathieu, Levings, Megan K., Zaph, Colby
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001530/
https://ncbi.nlm.nih.gov/pubmed/24667637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69592
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