Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

The pathogenic mechanisms underlying the progression of non-alcoholic fatty liver disease (NAFLD) are not fully understood. In this study, we aimed to assess the relationship between endoplasmic reticulum (ER) stress and autophagy in human and mouse hepatocytes during NAFLD. ER stress and autophagy...

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Détails bibliographiques
Auteurs principaux: González-Rodríguez, Á, Mayoral, R, Agra, N, Valdecantos, M P, Pardo, V, Miquilena-Colina, M E, Vargas-Castrillón, J, Lo Iacono, O, Corazzari, M, Fimia, G M, Piacentini, M, Muntané, J, Boscá, L, García-Monzón, C, Martín-Sanz, P, Valverde, Á M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001315/
https://ncbi.nlm.nih.gov/pubmed/24743734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.162
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