The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8(+) T cells

The transcription factor BATF is required for interleukin 17 (IL-17)-producing helper T cell (T(H)17) and follicular helper T cell (T(FH)) differentiation. Here, we show that BATF also has a fundamental role in regulating effector CD8(+) T cell differentiation. BATF-deficient CD8(+) T cells show pro...

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Detalhes bibliográficos
Main Authors: Kurachi, Makoto, Barnitz, R. Anthony, Yosef, Nir, Odorizzi, Pamela M., Dilorio, Michael A., Lemieux, Madeleine E., Yates, Kathleen, Godec, Jernej, Klatt, Martin G., Regev, Aviv, Wherry, E. John, Haining, W. Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000237/
https://ncbi.nlm.nih.gov/pubmed/24584090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2834
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