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The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8(+) T cells
The transcription factor BATF is required for interleukin 17 (IL-17)-producing helper T cell (T(H)17) and follicular helper T cell (T(FH)) differentiation. Here, we show that BATF also has a fundamental role in regulating effector CD8(+) T cell differentiation. BATF-deficient CD8(+) T cells show pro...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000237/ https://ncbi.nlm.nih.gov/pubmed/24584090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2834 |
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