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Opposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance

The interplay between molecular chaperones, ubiquitin/deubiquitinating enzymes, and proteasomes is a critical element in protein homeostasis. Among these factors, the conserved deubiquitinase, Ubp3, has the interesting ability, when overproduced, to suppress the requirement for the major cytosolic H...

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Autores principales: Öling, David, Eisele, Frederik, Kvint, Kristian, Nyström, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000091/
https://ncbi.nlm.nih.gov/pubmed/24596250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386822
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