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Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs

Endocytic down-regulation of cell-surface proteins is a fundamental cellular process for cell survival and adaptation to environmental stimuli. Ubiquitination of cargo proteins serves as the sorting signal for downstream trafficking and relies on the arrestin-related trafficking adaptor (ART)-Rsp5 u...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Ho, Hsuan-Chung, MacGurn, Jason A., Emr, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415021/
https://ncbi.nlm.nih.gov/pubmed/28298493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0008
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