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Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation
Nuclear localization of non-phosphorylated, active β-catenin is a measure of Wnt pathway activation and is associated with adverse outcome in patients with acute myeloid leukemia (AML). While genetic alterations of the Wnt pathway are infrequent in AML, inhibitors of this pathway are silenced by pro...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000011/ https://ncbi.nlm.nih.gov/pubmed/20795789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2010.496505 |
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