Epigenetic differences in cytogenetically normal versus abnormal acute myeloid leukemia

Methylation of tumor suppression genes (TSGs) is common in myeloid malignancies. However, application of this as a molecular marker for risk stratification in patients with AML is limited. To elucidate the impact of patterns of TSG methylation on outcome in cytogenetically normal patients, 106 sampl...

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Detalhes bibliográficos
Main Authors: Griffiths, Elizabeth A, Gore, Steven D, Hooker, Craig M, Mohammad, Helai P, McDevitt, Michael A, Smith, B Douglas, Karp, Judith E, Herman, James G, Carraway, Hetty E
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052845/
https://ncbi.nlm.nih.gov/pubmed/20671427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.5.7.12558
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