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Core binding factor beta-smooth muscle myosin heavy chain chimeric protein involved in acute myeloid leukemia forms unusual nuclear rod-like structures in transformed NIH 3T3 cells.

Patients with the M4Eo subtype of acute myeloid leukemia almost invariably are found to have an inversion of chromosome 16 in their leukemic cells, which results in a gene fusion between the transcription factor called core binding factor beta (CBFbeta) on 16q and a smooth muscle myosin heavy chain...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wijmenga, C, Gregory, P E, Hajra, A, Schröck, E, Ried, T, Eils, R, Liu, P P, Collins, F S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1630
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