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Phosphatidylinositol-4,5-Bisphosphate Enhances Anionic Lipid Demixing by the C2 Domain of PKCα

The C2 domain of PKCα (C2α) induces fluorescence self-quenching of NBD-PS in the presence of Ca(2+), which is interpreted as the demixing of phosphatidylserine from a mixture of this phospholipid with phosphatidylcholine. Self-quenching of NBD-PS was considerably increased when phosphatidylinositol-...

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Bibliographische Detailangaben
Hauptverfasser: Egea-Jiménez, Antonio L., Fernández-Martínez, Ana M., Pérez-Lara, Ángel, de Godos, Ana, Corbalán-García, Senena, Gómez-Fernández, Juan C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999146/
https://ncbi.nlm.nih.gov/pubmed/24763383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095973
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