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A Role for Sphingomyelin-Rich Lipid Domains in the Accumulation of Phosphatidylinositol-4,5-Bisphosphate to the Cleavage Furrow during Cytokinesis

Cytokinesis is a crucial step in the creation of two daughter cells by the formation and ingression of the cleavage furrow. Here, we show that sphingomyelin (SM), one of the major sphingolipids in mammalian cells, is required for the localization of phosphatidylinositol-4,5-bisphosphate (PIP(2)) to...

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Autores principales: Abe, Mitsuhiro, Makino, Asami, Hullin-Matsuda, Françoise, Kamijo, Keiju, Ohno-Iwashita, Yoshiko, Hanada, Kentaro, Mizuno, Hideaki, Miyawaki, Atsushi, Kobayashi, Toshihide
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318597/
https://ncbi.nlm.nih.gov/pubmed/22331463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06113-11
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