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Characterization of Genomic Vitamin D Receptor Binding Sites through Chromatin Looping and Opening

The vitamin D receptor (VDR) is a transcription factor that mediates the genomic effects of 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). Genome-wide there are several thousand binding sites and hundreds of primary 1,25(OH)(2)D(3) target genes, but their functional relation is largely elusive. In t...

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書目詳細資料
Main Authors: Seuter, Sabine, Neme, Antonio, Carlberg, Carsten
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999108/
https://ncbi.nlm.nih.gov/pubmed/24763502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096184
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