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Characterization of Genomic Vitamin D Receptor Binding Sites through Chromatin Looping and Opening
The vitamin D receptor (VDR) is a transcription factor that mediates the genomic effects of 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). Genome-wide there are several thousand binding sites and hundreds of primary 1,25(OH)(2)D(3) target genes, but their functional relation is largely elusive. In t...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3999108/ https://ncbi.nlm.nih.gov/pubmed/24763502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096184 |
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