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Folliculin Regulates Ampk-Dependent Autophagy and Metabolic Stress Survival

Dysregulation of AMPK signaling has been implicated in many human diseases, which emphasizes the importance of characterizing AMPK regulators. The tumor suppressor FLCN, responsible for the Birt-Hogg Dubé renal neoplasia syndrome (BHD), is an AMPK-binding partner but the genetic and functional links...

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Bibliografische gegevens
Hoofdauteurs: Possik, Elite, Jalali, Zahra, Nouët, Yann, Yan, Ming, Gingras, Marie-Claude, Schmeisser, Kathrin, Panaite, Lorena, Dupuy, Fanny, Kharitidi, Dmitri, Chotard, Laëtitia, Jones, Russell G., Hall, David H., Pause, Arnim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998892/
https://ncbi.nlm.nih.gov/pubmed/24763318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004273
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