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Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity

Female meiosis is driven by the activities of two major kinases, cyclin-dependent kinase 1 (Cdk1) and mitogen-activated protein kinase (MAPK). To date, the role of MAPK in control of meiosis is thought to be restricted to maintaining metaphase II arrest through stabilizing Cdk1 activity. In this pap...

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Detalhes bibliográficos
Main Authors: Nabti, Ibtissem, Marangos, Petros, Bormann, Jenny, Kudo, Nobuaki R., Carroll, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3998794/
https://ncbi.nlm.nih.gov/pubmed/24637322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201305049
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