Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II

In mitosis, the Greatwall kinase (called microtubule-associated serine/threonine kinase like [Mastl] in mammals) is essential for prometaphase entry or progression by suppressing protein phosphatase 2A (PP2A) activity. PP2A suppression in turn leads to high levels of Cdk1 substrate phosphorylation....

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Detalhes bibliográficos
Main Authors: Adhikari, Deepak, Diril, M. Kasim, Busayavalasa, Kiran, Risal, Sanjiv, Nakagawa, Shoma, Lindkvist, Rebecca, Shen, Yan, Coppola, Vincenzo, Tessarollo, Lino, Kudo, Nobuaki R., Kaldis, Philipp, Liu, Kui
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178961/
https://ncbi.nlm.nih.gov/pubmed/25246615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406033
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