Inhibitory phosphorylation of Cdk1 mediates prolonged prophase I arrest in female germ cells and is essential for female reproductive lifespan

A unique feature of female germ cell development in mammals is their remarkably long arrest at the prophase of meiosis I, which lasts up to 50 years in humans. Both dormant and growing oocytes are arrested at prophase I and completely lack the ability to resume meiosis. Here, we show that the prolon...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Adhikari, Deepak, Busayavalasa, Kiran, Zhang, Jingjing, Hu, Mengwen, Risal, Sanjiv, Bayazit, Mustafa Bilal, Singh, Meenakshi, Diril, M Kasim, Kaldis, Philipp, Liu, Kui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099868/
https://ncbi.nlm.nih.gov/pubmed/27767095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.119
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados