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Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1)

Mammalian oocytes are arrested in prophase of the first meiotic division. Progression into the first meiotic division is driven by an increase in the activity of maturation-promoting factor (MPF). In mouse oocytes, we find that early mitotic inhibitor 1 (Emi1), an inhibitor of the anaphase-promoting...

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Bibliographic Details
Main Authors: Marangos, Petros, Verschuren, Emmy W., Chen, Ruby, Jackson, Peter K., Carroll, John
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063628/
https://ncbi.nlm.nih.gov/pubmed/17190794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200607070
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