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Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1)

Mammalian oocytes are arrested in prophase of the first meiotic division. Progression into the first meiotic division is driven by an increase in the activity of maturation-promoting factor (MPF). In mouse oocytes, we find that early mitotic inhibitor 1 (Emi1), an inhibitor of the anaphase-promoting...

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Detalhes bibliográficos
Main Authors: Marangos, Petros, Verschuren, Emmy W., Chen, Ruby, Jackson, Peter K., Carroll, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063628/
https://ncbi.nlm.nih.gov/pubmed/17190794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200607070
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