Toll-like Receptor Polymorphism Associations With HIV-1 Outcomes Among Sub-Saharan Africans

Objective. We evaluated Toll-like receptors (TLRs) single nucleotide polymorphisms (SNPs) for associations with HIV-1 acquisition, set-point and disease progression in African couples. Methods. Seven candidate and 116 haplotype-tagging SNPs (tagSNPs) were genotyped in 504 HIV-1 infected cases, and 3...

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Detalhes bibliográficos
Main Authors: Mackelprang, Romel D., Bigham, Abigail W., Celum, Connie, de Bruyn, Guy, Beima-Sofie, Kristin, John-Stewart, Grace, Ronald, Allan, Mugo, Nelly R., Buckingham, Kati J., Bamshad, Michael J., Mullins, James I., McElrath, M. Juliana, Lingappa, Jairam R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997584/
https://ncbi.nlm.nih.gov/pubmed/24325963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit807
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