Variants in Host Viral Replication Cycle Genes Are Associated With Heterosexual HIV-1 Acquisition in Africans

OBJECTIVE: We evaluated genetic variants in 51 candidate genes encoding proteins that interact with HIV-1 during the virus life cycle for association with HIV-1 outcomes in an African cohort. METHODS: Using a nested case–control study within a cohort of heterosexual HIV-1–serodiscordant couples, we...

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Detalhes bibliográficos
Main Authors: Bigham, Abigail W., Mackelprang, Romel D., Celum, Connie, Bruyn, Guy De, Beima-Sofie, Kristin, John-Stewart, Grace, Ronald, Allan, Mugo, Nelly R., Buckingham, Kati, Bamshad, Michael J., Mullins, James I., McElrath, M. J., Lingappa, Jairam R.
Formato: Artigo
Idioma:Inglês
Publicado em: JAIDS Journal of Acquired Immune Deficiency Syndromes 2014
Assuntos:
Basic and Translational Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025588/
https://ncbi.nlm.nih.gov/pubmed/24463784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000113
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