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Retrotransposon Hypomethylation in Melanoma and Expression of a Placenta-Specific Gene

In the human placenta, DNA hypomethylation permits the expression of retrotransposon-derived genes that are normally silenced by methylation in somatic tissues. We previously identified hypomethylation of a retrotransposon-derived transcript of the voltage-gated potassium channel gene KCNH5 that is...

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Detalhes bibliográficos
Main Authors: Macaulay, Erin C., Roberts, Hester E., Cheng, Xi, Jeffs, Aaron R., Baguley, Bruce C., Morison, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997481/
https://ncbi.nlm.nih.gov/pubmed/24759919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095840
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