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Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements

The human placenta is hypomethylated compared to somatic tissues. However, the degree and specificity of placental hypomethylation across the genome is unclear. We assessed genome-wide methylation of the human placenta and compared it to that of the neutrophil, a representative homogeneous somatic c...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Chatterjee, Aniruddha, Macaulay, Erin C., Rodger, Euan J., Stockwell, Peter A., Parry, Matthew F., Roberts, Hester E., Slatter, Tania L., Hung, Noelyn A., Devenish, Celia J., Morison, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938645/
https://ncbi.nlm.nih.gov/pubmed/27172225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.030379
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