MITF and PAX3 Play Distinct Roles in Melanoma Cell Migration; Outline of a “Genetic Switch” Theory Involving MITF and PAX3 in Proliferative and Invasive Phenotypes of Melanoma

Melanoma is a very aggressive neoplasm with a propensity to undergo progression and invasion early in its evolution. The molecular pathways underpinning invasion in melanoma are now just beginning to be elucidated, but a clear understanding of the transition from non-invasive to invasive melanoma ce...

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Detalhes bibliográficos
Main Authors: Eccles, Michael R., He, Shujie, Ahn, Antonio, Slobbe, Lynn J., Jeffs, Aaron R., Yoon, Han-Seung, Baguley, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769631/
https://ncbi.nlm.nih.gov/pubmed/24062982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00229
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