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Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T-cells

The clinical success of allogeneic T-cell therapy for cancer relies on the selection of antigens that can effectively elicit antitumor responses with minimal toxicity toward nonmalignant tissues. While minor histocompatibility antigens (MiHA) represent promising targets, broad expression of these an...

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Detalhes bibliográficos
Main Authors: Shand, Jessica C., Qin, Haiying, Nasholm, Nicole, Capitini, Christian M., Fry, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997266/
https://ncbi.nlm.nih.gov/pubmed/24141010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.10.009
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