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Site-specific accumulation of recently activated CD4(+)Foxp3(+) regulatory T cells following adoptive transfer
CD4(+)Foxp3(+) regulatory T cells (Tregs) are required for maintenance of self-tolerance, as demonstrated by profound autoimmunity in mice and humans with inactivating Foxp3 mutations. Recent studies demonstrate that Tregs are anatomically compartmentalized within secondary lymphoid organs based on...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3664195/ https://ncbi.nlm.nih.gov/pubmed/22678899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142286 |
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