STAT3 Genotypic Variation and Cellular STAT3 Activation and Colon Leukocyte Recruitment in Pediatric Crohn Disease

OBJECTIVES: Genotypic variation in STAT3 increases risk for IBD, and STAT3 dependent inflammatory networks are induced in the colon in these patients. We hypothesized that STAT3 “A” risk allele carriage would be associated with increased cellular STAT3 activation and colon leukocyte recruitment. MET...

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Main Authors:	Willson, Tara A., Kuhn, Benjamin R., Jurickova, Ingrid, Gerad, Shaina, Moon, David, Bonkowski, Erin, Carey, Rebecca, Collins, Margaret, Xu, Huan, Jegga, Anil G., Guthery, Stephen L., Denson, Lee A.
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3996847/ https://ncbi.nlm.nih.gov/pubmed/22197944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0b013e318246be78
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STAT3 Genotypic Variation and Cellular STAT3 Activation and Colon Leukocyte Recruitment in Pediatric Crohn Disease

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