Lipopolysaccharide Exposure is Linked to Activation of the Acute Phase Response and Growth Failure in Pediatric Crohn’s Disease and Murine Colitis

BACKGROUND: Systemic exposure to lipopolysaccharide (LPS) has been linked to clinical disease activity in adults with IBD. We hypothesized that markers of LPS exposure and the acute phase response (APR) would be increased in pediatric IBD patients with growth failure, and that LPS signaling would be...

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Detalhes bibliográficos
Main Authors: Pasternak, Brad A., D’Mello, Sharon, Jurickova, Ingrid I., Han, Xiaonan, Willson, Tara, Flick, Leah, Petiniot, Lisa, Uozumi, Naonori, Divanovic, Senad, Traurnicht, Anna, Bonkowski, Erin, Kugathasan, Subra, Karp, Christopher L., Denson, Lee A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052288/
https://ncbi.nlm.nih.gov/pubmed/19924809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21132
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