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Deletion of Intestinal Epithelial Cell STAT3 Promotes T Lymphocyte STAT3 Activation and Chronic Colitis Following Acute Dextran Sodium Sulfate Injury in Mice

BACKGROUND: Intestinal epithelial cell (IEC) Stat3 is required for wound healing following acute Dextran Sodium Sulfate (DSS) injury. We hypothesized that loss of IEC STAT3 would promote the development of chronic colitis following acute DSS injury. METHODS: Colitis was induced in IEC-specific Stat3...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Willson, Tara A., Jurickova, Ingrid, Collins, Margaret, Denson, Lee A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330009/
https://ncbi.nlm.nih.gov/pubmed/23429443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e31828028ad
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