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Targeted deletion of Atg5 in intestinal epithelial cells promotes dextran sodium sulfate-induced colitis
Autophagy-associated genes have been identified as susceptible loci for inflammatory bowel disease. We investigated the role of a core autophagy factor, Atg5, in the development of dextran sodium sulfate (DSS)-induced colitis. Intestinal epithelial cell (IEC)-specific Atg5 gene deficient mice (Atg5(...
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| Udgivet i: | J Clin Biochem Nutr |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
the Society for Free Radical Research Japan
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8045999/ https://ncbi.nlm.nih.gov/pubmed/33879967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.20-90 |
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