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Rapid onset and reversal of peripheral and central leptin resistance in rats offered chow, sucrose solution, and lard()

We previously reported that rats offered choice diet (chow, 30% sucrose solution, lard) increase body fat by 130% within 3 weeks. We tested the effects of choice diet on the development of leptin resistance in rats. Intraperitoneal injection of 2 mg/kg leptin inhibited 14 h food intake and weight ga...

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Autors principals: Apolzan, John W., Harris, Ruth B.S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996830/
https://ncbi.nlm.nih.gov/pubmed/23022555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.appet.2012.09.020
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